Metal–organic frameworks
Synthesis, radiolabeling, and biomedical use of ZIF-8, MIL-100(Fe), and related nanoscale MOFs for imaging and therapy.
Laboratory
Research
The program combines experimental nanomedicine with machine learning: designing MOF-based carriers, tracking them in vivo, and predicting how nanomaterials behave in biological systems.
AI in nanomedicine
Machine learning for nanoparticle toxicity, protein corona, drug loading, pharmacokinetics, and formulation design.
Targeted drug delivery
Nanocarriers for cancer, rheumatoid arthritis, infection, and wound healing, including theranostic platforms.
Tissue engineering
Hydrogels, scaffolds, and hybrid biomaterials that combine nanotechnology with regenerative approaches.
Grants & funded projects
Role: Co-PI
Wood with ZIF-8/rosuvastatin and mucilage for bone regeneration
Shahid Beheshti University of Medical Sciences
Ethics / contract: IR.SBMU.PHARMACY.REC.1404.218
Role: Co-PI
Chitosan–gelatin hydrogel containing exosomes and rosemary extract for diabetic wound healing
Shahid Beheshti University of Medical Sciences
Ethics / contract: IR.SBMU.AEC.1404.113
Role: Co-PI
AI-based tools for nanomedicine and precision pharmaceuticals
Shahid Beheshti University of Medical Sciences
Ethics / contract: IR.SBMU.PHARMACY.REC.1404.265
Role: PI
Predicting porosity of chitosan-based hydrogels in tissue engineering using machine learning
Shahid Beheshti University of Medical Sciences
Ethics / contract: IR.SBMU.RETECH.REC.1404.461
Role: PI
Predicting and simulating chemotherapy drug interactions with machine learning and molecular docking
Shahid Beheshti University of Medical Sciences
Ethics / contract: IR.SBMU.RETECH.REC.1404.135
Role: PI
Protein corona on nanoparticles and AI-based composition prediction (review)
Shahid Beheshti University of Medical Sciences
Ethics / contract: IR.SBMU.RETECH.REC.1404.022
Role: Co-PI
AI for anticipating ZIF-8 nanostructure attributes with experimental evaluation
Shahid Beheshti University of Medical Sciences
Ethics / contract: IR.SBMU.PHARMACY.REC.1403.288
Role: Co-PI
ZIF-8@MXene nanosystem for metformin delivery in breast cancer
Shahid Beheshti University of Medical Sciences
Ethics / contract: IR.SBMU.PHARMACY.REC.1402.238
Role: PI
Predicting aqueous solubility of chemical compounds by machine learning for drug design
Shahid Beheshti University of Medical Sciences
Ethics / contract: IR.SBMU.RETECH.REC.1404.460
Role: PI
Prediction of loading capacity of polymeric nanoparticles using machine learning
Shahid Beheshti University of Medical Sciences
Ethics / contract: IR.SBMU.PHARMACY.REC.1404.026
Role: Co-PI
ZIF-8 loaded with levofloxacin on Pseudomonas aeruginosa isolates from children with cystic fibrosis
Shahid Beheshti University of Medical Sciences
Ethics / contract: IR.SBMU.MSP.REC.1403.143
Role: Co-PI
Machine learning-assisted rheumatoid arthritis formulations
Shahid Beheshti University of Medical Sciences
Ethics / contract: IR.SBMU.PHARMACY.REC.1403.083
Role: Co-PI
Strategies to design biobetters: pharmacodynamics and pharmacokinetics
Shahid Beheshti University of Medical Sciences
Ethics / contract: IR.SBMU.PHARMACY.REC.1403.145
Role: Co-PI
AI model to predict therapeutic response to DMARDs
Shahid Beheshti University of Medical Sciences
Ethics / contract: IR.SBMU.RETECH.REC.1403.329
Role: PI
Predicting the efficiency of nanoliposomes in cancer treatment using machine learning
Red Crescent Society of the Islamic Republic of Iran (industry collaboration)
Role: Co-PI
Predicting efficacy of gold nanostructures in photothermal therapy using AI
Shahid Beheshti University of Medical Sciences
Ethics / contract: IR.SBMU.RETECH.REC.1402.836
Role: PI
Predicting pharmacokinetics of drugs using artificial intelligence tools: a systematic review
Shahid Beheshti University of Medical Sciences
Ethics / contract: IR.SBMU.RETECH.REC.1401.716
Role: Co-inv
Prediction of ovarian cancer using artificial intelligence tools
Tehran University of Medical Sciences
Ethics / contract: IR.TUMS.SPH.REC.1401.277
Role: Co-PI
Toxicity prediction of nanoparticles using data mining approaches
Shahid Beheshti University of Medical Sciences
Ethics / contract: IR.SBMU.PHARMACY.REC.1401.291
Role: Co-inv
Application of metal–organic framework ZIF-8 in methotrexate delivery
Shahid Beheshti University of Medical Sciences
Ethics / contract: IR.SBMU.PHARMACY.REC.1400.078
Role: Co-inv
MIL-100(Fe) in methotrexate delivery to rheumatoid arthritis
Shahid Beheshti University of Medical Sciences
Ethics / contract: IR.SBMU.PHARMACY.REC.1400.245
Role: Co-PI
Radiolabeling of MOFs and in vivo SPECT imaging
Shahid Beheshti University of Medical Sciences
Ethics / contract: IR.SBMU.PHARMACY.REC.1399.151
Role: Co-PI
Labeling of MOF with technetium-99m for diagnostic purposes
NIMAD
Ethics / contract: Contract 988055
Thesis supervision
2025–now
In progress
UIO-66-NH2@CS-HA nanoparticles for metformin and D-limonene delivery in breast cancer
Student: Mehdi Karimi Khanghah · Pharm.D.
2023–now
In progress
ZIF-8 loaded with levofloxacin on Pseudomonas aeruginosa isolates from children with cystic fibrosis
Student: Sara Bahonar · Ph.D. in Microbiology
2023–now
In progress
ZIF-8 containing ciprofloxacin and antibacterial evaluation
Student: Moin Farnia · Pharm.D.
2024–2025
Completed
AI-assisted microfluidic ZIF-8 synthesis for osteo-regeneration in a wood/quince-seed mucilage scaffold
Student: Niki Pouyanfar · Ph.D. in Pharmaceutics
2023–2025
Completed
Mupirocin@ZIF-8 in basil-seed mucilage for secondary skin infection in atopic dermatitis
Student: Hasti Sepahi · Pharm.D.
2023–2025
Completed
ZIF-8@MXene nanosystem for metformin delivery in breast cancer
Student: Niloofar Masoumi · Pharm.D.
2020–now
In progress
MIP based on MOFs for extraction of benzodiazepines in biological fluids
Student: Ramin Shokrekhoda · Pharm.D.
2020–2022
Completed
pH-sensitive ZIF-8 for methotrexate delivery in rheumatoid arthritis
Student: Reyhane Masoudifar · Pharm.D.
2020–2022
Completed
MIL-100(Fe) for methotrexate delivery in rheumatoid arthritis
Student: Niki Pouyanfar · Pharm.D.